• Author: Norman Doidge
• Paperback: 448 pages
• Publisher: Penguin (Non-Classics); 1 edition (December 18, 2007)
• ISBN-10: 0143113100

A collection of anecdotes about doctors and patients demonstrating that the human brain is capable of undergoing remarkable changes. Research psychiatrist and psychoanalyst Doidge (Columbia Univ. Psychoanalytic Center) calls this growing awareness of the brain's adaptability "the neuroplastic revolution," and he profiles scientists whose work in neuroplasticity has changed people's lives. He begins with Paul Bach-y-Rita, a pioneer in brain plasticity who has helped stroke victims improve their balance and walking. Doidge also interviews Michael Merzenich, a researcher and inventor who claims that brain exercises may be as useful as drugs in treating schizophrenia and has also developed training programs for the learning-disabled and the aging. The author talks with V.S. Ramachandran, a neurologist successful in treating phantom-limb pain, and he visits the Salk Laboratories in La Jolla, Calif., to report on the implications of current research on human neuronal stem cells. Some stories focus on nonscientists, such as the brain-damaged woman who developed her own brain exercises and then founded a Toronto school for children with learning disabilities, and a woman who functions well and has extraordinary calculating skills despite her brain having virtually no left hemisphere. The author draws on his own psychoanalytic practice to illustrate how the brain's plasticity can also create problems, e.g., when early childhood trauma causes massive change in a patient's hippocampus. One appendix explores the issue of how culture shapes the brain and is shaped by it; another takes a brief look at changing ideas about human nature and its perfectibility. Somewhat scattershot, but Doidge's personalstories, enthusiasm for his subject and admiration for its researchers keep the reader engaged.

(Source: Kirkus Reviews)

For years the doctrine of neuroscientists has been that the brain is a machine: break a part and you lose that function permanently. But more and more evidence is turning up to show that the brain can rewire itself, even in the face of catastrophic trauma: essentially, the functions of the brain can be strengthened just like a weak muscle. Scientists have taught a woman with damaged inner ears, who for five years had had "a sense of perpetual falling," to regain her sense of balance with a sensor on her tongue, and a stroke victim to recover the ability to walk although 97% of the nerves from the cerebral cortex to the spine were destroyed. With detailed case studies reminiscent of Oliver Sachs, combined with extensive interviews with lead researchers, Doidge, a research psychiatrist and psychoanalyst at Columbia and the University of Toronto, slowly turns everything we thought we knew about the brain upside down. He is, perhaps, overenthusiastic about the possibilities, believing that this new science can fix every neurological problem, from learning disabilities to blindness. But Doidge writes interestingly and engagingly about some of the least understood marvels of the brain.

(Source: Publishers Weekly)

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